CHILDHOOD-ONSET GRAVES’ DISEASE

Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016

Purpose behind developing these guidelines: Over one decade ago, the "Guidelines for the Treatment of Graves' Disease with Antithyroid Drug, 2006" (Japan Thyroid Association (JTA)) were published as the standard drug therapy protocol for Graves' disease. The "Guidelines for the Treatment of Childhood-Onset Graves' Disease with Antithyroid Drug in Japan, 2008" were published to provide guidance ...

Five cases of childhood-onset Graves’ disease treated with either surgery or radio-iodine therapy

There are three major therapeutic options for the treatment of Graves' disease (GD): antithyroid drugs (ATDs), thyroidectomy, and radio-iodine (RAI) therapy. ATDs are the initial treatment option for children. However, some pediatric GD patients who are initially treated with ATDs require other type of treatments later on. We reviewed the medical records of childhood-onset GD cases retrospectiv...

New-onset Graves' disease in the postpartum period.

During routine evaluation for lactation failure, hyperthyroidism was discovered in a postpartum woman. Although postpartum thyroiditis and Hashimoto's disease are relatively more common than Graves' disease during the postnatal period, this young woman was found to have new-onset Graves' disease. Distinguishing between normal postpartum symptoms and thyroid disorders can be challenging. Utilizi...

Early-onset breast cancer in a woman with Graves' disease.

The relationship between thyroid and breast diseases has been documented, but the clinical significance of Graves' disease and breast cancer is unclear. We present a young patient with a history of Graves' disease who developed a multicentric infiltrating ductal carcinoma of the breast several months after discontinuing her treatment with propylthiouracil. Early-onset breast cancer in women wit...

[Graves' disease].